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Ideal candidates typically include: Body composition goals: Individuals focused on reducing body fat percentage while preserving lean muscle mass, those who have reached plateaus with diet and exercise alone, patients seeking metabolically selective approaches without growth hormones broader effects, or individuals interested in targeted fat reduction (particularly abdominal/visceral fat)

Here, it is focused to investigate the role of these associated signaling pathways that inhibit ferroptosis

In addition, berberine can properly restore the levels of 3-nitrotyrosine (3-NT), COX 2, glial fibrillary acidic protein (GFAP), and sirtuin 1 in the hippocampus (Sadraie et al., 2019)

Mitochondrial fission in apoptosis